6-Methoxy-pyrazine-2-carbothioic acid amide - Names and Identifiers
6-Methoxy-pyrazine-2-carbothioic acid amide - Physico-chemical Properties
Molecular Formula | C6H7N3OS
|
Molar Mass | 169.2 |
Density | 1.338 |
Melting Point | 217-218℃ |
Boling Point | 314℃ |
Flash Point | 144℃ |
Vapor Presure | 0.000466mmHg at 25°C |
Refractive Index | 1.635 |
6-Methoxy-pyrazine-2-carbothioic acid amide - Introduction
Pyrazinecarbothioamide, 6-methoxy-is an organic compound with the chemical formula C6H7N3OS, which has the form of a white solid. The following is a detailed description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: White solid
-Molecular weight: 173.21g/mol
-melting point: 129-131 ℃
-boiling point: 255-258 ℃
-Soluble: Soluble in certain organic solvents such as ammonia and chloroform
-Stability: stable under normal storage conditions, avoid prolonged exposure to air
Use:
Pyrazinecarbothioamide, 6-methoxy-has applications in chemical research and the pharmaceutical industry:
-As an intermediate in organic synthesis, it can be used to synthesize other compounds
-Can be used to prepare biologically active organic compounds, such as drugs and pesticides
Preparation Method:
Pyrazinecarbothioamide, there are many ways to prepare 6-methoxy-, the following is a possible synthetic route:
1. Dissolve pyrazine in hot thioformamide.
2. During the heating process, slowly add methoxy bromide.
3. After completion of the reaction, the mixture was cooled and an appropriate amount of water was added.
4. The organic layer was extracted with ether and dried with anhydrous sodium chloride.
5. Crystallization to obtain pure Pyrazinecarbothioamide, 6-methoxy-.
Safety Information:
Pyrazinecarbothioamide, 6-methoxy-has low toxicity under general operating conditions. However, general laboratory safety practices should be followed when using and handling chemicals, including the wearing of appropriate protective equipment (such as gloves, glasses, and laboratory suits). During storage, it should be kept dry and sealed to avoid contact with oxygen, moisture and strong oxidants. If exposed or ingested, medical help should be sought immediately.
Last Update:2024-04-09 20:45:29